Pancreatic Essay

Pancreatic Essay-4
Therefore, it is necessary to evaluate new therapeutic approaches.

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Therefore new efforts have to be made in the field of translational oncology to improve the understanding, the diagnosis and the therapy of this disease.

Apart from PDAC there are other pancreatic cancer types, which differ highly in patient outcome due to their tissue origin and genetic make up.

MUC-1 and u PA are strongly expressed on CFPAC-1, PANC-1 and moderate expression was found CAPAN-1 cell clusters and tumor xenografts.

The ACs can target pancreatic cells and regress cell clusters (~100 µm diameter), causing apoptosis in some 70–90 % of cells.

These low survival rates demonstrate the poor prognosis of this carcinoma.

Previous therapeutic approaches including surgical resection combined with adjuvant therapy or palliative chemoradiation have not achieved satisfactory results with respect to overall survival.Please select whether you prefer to view the MDPI pages with a view tailored for mobile displays or to view the MDPI pages in the normal scrollable desktop version.This selection will be stored into your cookies and used automatically in next visits.Cancers like intraductal papillary mucinous neoplasia are of growing concern to the physicians and researchers in the field.This issue will focus on the recent key findings in the field of pancreatic cancer research and therapy.It will contain different articles regarding the different types of pancreatic cancer, the latest research and new strategies to improve the therapy of this disease. Christian Pilarsky Pancreatic cancer does not respond to a single-agent imatinib therapy.Consequently, multimodality treatments are contemplated. Published data indicate that in colorectal cancer, imatinib and radioimmunotherapy synergize to delay tumor growth.Pancreatic cancer does not respond to a single-agent imatinib therapy.This disparity of outcomes merited further studies because interactions between these modalities depend on the imatinib-induced reduction of the tumor interstitial fluid pressure.Mice were injected with different concentrations of AC by local or systemic administration.Changes in tumor progression were assessed by tumor size.


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