Literature Review On Depression

It is considered to be the major cause of years lived with disability (YLD) and by 2020 is expected to be among the two main causes of disability adjusted years (DALYs) together with ischemic heart disease [4].The functional limitations caused by depression are equal to or even sometimes greater than the ones engendered by many other chronic medical conditions [5].In spite of the great advances achieved in treatment of depression during the last decades, between 20 and 30% of cases are not adequately solved by first agent treatments (also known as treatment-resistant depression in literature) [6].

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Literature reported the main psychosocial difficulties almost fully, but not in the same degree of importance as patients’ reports.

Furthermore, the covered areas were very general and related to symptomatology.

Psychosocial difficulties were defined according to the World Health Organization International Classification of Functioning, Disability and Health (ICF).

A comparative approach between a systematic literature review, a focus group, and individual interviews with depressed patients was used.

Despite all the knowledge on depression, it is still unclear whether current literature covers all the psychosocial difficulties (PSDs) important for depressed patients.

The aim of the present study was to identify the gaps in the recent literature concerning PSDs and their related variables.Furthermore, identification of interventions for particular psychosocial difficulties and personalisation of therapies according to individuals’ PSDs are necessary.Depression is a major public health issue due to its prevalence, high mortality rates [1], suicide risk [2], and economic impact on the society [3].There are few existing studies using qualitative research to identify a full list of PSDs which depressed people experience.Yet, none of them has applied a comprehensive approach in order to encompass all the psychosocial difficulties from different perspectives. [12], which aimed to develop a specific questionnaire to assess symptoms for adult major depressive patients and to track their functional status.The aim of the present study is to tackle this research gap and discover whether the recent scientific literature actually reports the PSDs and their related variables that are important for depressed patients.Our objective is to obtain information about whether the latest literature extensively covers the issues that are pointed out as problematic by depressed individuals, or if there are particular areas, which should receive more attention.Instituto de Investigación de la Princesa (IIS-IP), Hospital Universitario de la Princesa, C/Diego de León 62, 28006 Madrid, Spain Received 4 February 2014; Revised ; Accepted ; Published 9 June 2014Academic Editor: François Beck Copyright © 2014 Kaloyan Kamenov et al.This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.The majority of studies on this topic are quantitative; however, the literature that uses qualitative methodologies—which could provide deeper, richer, and more elaborated data, exploratory analyses on patients’ needs and standpoints, and thus more objective results—is sparse.Furthermore, this kind of studies can provide a general view if particular psychosocial difficulties, named by patients as important, are missing in the literature.


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